Choosing between a label printer and a handheld label maker often comes down to where your labeling happens. In label makers supplies, you are really choosing between a workflow built around a computer and a workflow that follows you around. One is a printer; the other is a label maker. The Dymo Thermal Label Writer 4XL Label Printer With Power Supply & USB Labels represents the first approach, while the Label Maker Machine - Waterproof 12mm Labels, Easy-to-Use, Portable & Versatile (D210S) represents the second.
Quick Verdict
The Dymo LabelWriter 4XL is the $179.97 model; the D210S is the $59.99 model. If your labels are made at a desk and printed through a computer, the Dymo is the more appropriate choice. If you need a label maker that moves with you and handles creative projects, the D210S is the better fit.
Comparison Table
| Feature | Dymo LabelWriter 4XL | D210S Waterproof Label Maker |
|---|---|---|
| Price | $179.97 | $59.99 |
| Price bar | ||
| Condition | Used | New |
| Connectivity | USB | USB |
| Model | Dymo LabelWriter 4XL | D210S Label Maker |
| Print output | Black & White | Monochrome |
| Print technology | Thermal | Laminated Waterproof |
| Highlights | Power supply and USB labels included | Waterproof 12mm labels, built-in cutter, 800+ icons, 100+ borders, 16 fonts, continuous and dual-line printing |
Where Each Wins
The Dymo wins for a computer-based labeling workflow; it is the printer-first option. The D210S wins for on-the-go and creative labeling; it is the device you can move around and use for quick, custom labels. If you plan to do most labeling in one place, the Dymo is the stronger match. If you want one tool for organizing a pantry, making craft labels, or labeling on the spot, the D210S is the better companion.
Product Notes
Dymo Thermal Label Writer 4XL Label Printer With Power Supply & USB Labels
Get this if you want a dedicated USB label printer that uses thermal technology and black-and-white output. The 4XL is listed as used in good condition with normal signs of previous use, and it includes its power supply and USB labels, so it can sit on a desk and print without ink cartridges. The trade-off is the used condition and the fact that it's not a handheld device. If you are comfortable with a used thermal printer and need straightforward black-and-white labels, this is the one.
Label Maker Machine - Waterproof 12mm Labels, Easy-to-Use, Portable & Versatile
The D210S is the pick if you want a new label maker designed for waterproof 12mm labels. It uses laminated tapes and heat transfer technology, with labels described as resistant to scratches, oils, and temperatures from -40°F to 212°F, and durable for 10 years. It also has 800+ icons, 100+ borders, 16 fonts, one-touch editing, continuous printing, dual-line printing, and a built-in cutter. The limitation is the 12mm tape width and monochrome output. If your jobs call for a dedicated label printer rather than a handheld label maker, the Dymo LabelWriter 4XL is the better fit.
Final Choice by Use Case
For label printing that starts at a computer, choose the Dymo LabelWriter 4XL. For a creative, easy-to-use label maker that you can keep close by, choose the D210S.

